Have you switched any kind of equipment lately? Mouthpieces, trumpets, etc? If you changed mouthpieces, you should probably take your new one back if you can, since that likely means your problem is that your chops don`t match well with the mouthpiece.
Otherwise, it`s almost definitely an ambesure (<-- spelling?) problem. For a few days I would recommend playing only flow studies, long tones, and pedal tones for shortened practice periods. Stay away from higher notes whatever you do; if you have to play in school or something try to avoid playing anywhere above the staff and take it down an octave if you need to.
I would heavily emphasize pedal tones until the problem is fixed.
My guess if it`s an ambesure problem is that your mouthpiece is too low on your top lip, or not centered. You could also be using too much pressure; make sure your pinky is out of the ring and when you pull the horn away from your face there shouldn`t be a white ring where the mouthpiece was.
Some other less probable possibilities are that your corners are not firm enough for that register (make sure your cheeks, chin, or top lip areas don`t balloon with air when you play), or your lips are simply overworked (in which case you should probably not practice more than 10 minutes per day, and stay below the E in the staff in those practices).
Hope that helps